From Wikipedia,
the free encyclopedia
Pharmacogenomics is the
branch of
pharmaceutics which deals with
the influence of
genetic variation on drug
response in patients by
correlating
gene expression or
single-nucleotide polymorphisms
with a drug's
efficacy or
toxicity. By doing so,
pharmacogenomics aims to develop
rational means to optimise drug
therapy, with respect to the
patients'
genotype, to ensure maximum
efficacy with minimal
adverse effects. Such
approaches promise the advent of "personalised
medicine", in which drugs and
drug combinations are optimised
for each individual's unique
genetic makeup.
Pharmacogenomics is the whole
genome application of
pharmacogenetics, which
examines the single gene
interactions with drugs.
