From Wikipedia,
the free encyclopedia.
Information Hyperlinked over
Proteins (or iHOP) is
an online service that provides
this gene-guided network as a
natural way of accessing millions
of PubMed abstracts and brings all
the advantages of the internet to
scientific
literature research. By using
genes and
proteins as
hyperlinks between sentences
and abstracts, the information in
PubMed can be converted into
one navigable resource. Navigating
across interrelated sentences
within this network is closer to
human intuition than the use of
conventional
keyword searches and allows
for stepwise and controlled
acquisition of information.
Moreover, this literature network
can be superimposed upon
experimental interaction data to
facilitate the simultaneous
analysis of novel and existing
knowledge. The network presented
in iHOP currently contains 5
million sentences and 40000 genes
from
Homo sapiens,
Mus musculus,
Drosophila melanogaster,
Caenorhabditis elegans,
Danio rerio,
Arabidopsis thaliana,
Saccharomyces cerevisiae
and
Escherichia coli.
The system was published in
Nature Genetics 36, 664
(2004) as 'A gene network for
navigating the literature'.
