From Wikipedia,
the free encyclopedia.
Calreticulin is a
protein that binds
Ca2+
ions (a
second messenger
molecule in
signal transduction),
rendering it inactive. The Ca2+
is bound with low
affinity, but high
capacity, and can be released
on a signal (see
inositol triphosphate).
Calreticulin is located in storage
compartments associated with the
endoplasmic reticulum.
Calreticulin is also known as
calregulin, CRP55, CaBP3,
calsequestrin-like protein and
Ro/SS-A antigen.
