From Wikipedia,
the free encyclopedia.
Orf may also be a method of
instrumental
musical instruction that
approaches the basics of music
through the medium of
improvisation and eventually
note reading on instruments.
An open reading frame or
ORF is any
sequence of
DNA or
RNA that can be
translated into a protein. In
a
gene, ORFs are located between
the start-code sequence
(initiation codon) and the
stop-code sequence (termination
codon). ORFs are usually
encountered when sifting through
pieces of
DNA while trying to locate a
gene.
In fact, the existence of an
ORF, especially a long one, is
usually a good indication of the
presence of a gene in the
surrounding sequence. In this
case, the ORF is part of the
sequence that will be translated
by the
ribosomes and the ORF will be
long and continue over gaps, or
introns. However, short ORFs
can also occur by chance outside
of
genes. Usually ORFs outside
genes are not very long and
terminate after a few codons.
External links
-
NCBI ORF finder - A web
based interactive tool for
predicting and analysing ORFs
from nucleotide sequences.
-
ORF finder - A web based
interactive tool for predicting
and analysing ORFs from
nucleotide sequences - hosted at
bioinformatics.org
