From Wikipedia,
the free encyclopedia.
CASP, which stands for
Critical Assessment of
Techniques for Protein Structure
Prediction, is a
community-wide experiment (though
it is commonly referred to as a
competition) for
protein structure prediction
taking place every two years.
CASP provides research groups
with an opportunity to assess the
quality of their methods for
protein structure prediction
from the
primary structure of the
protein. As a consequence, CASP
provides the research community
with an assessment of the state of
the art in this field.
Protein structures that have
been recently resolved, but not
yet published, are used as targets
for the evaluation. If the given
sequence is found (for example,
using
sequence alignment methods
such as
BLAST or
FASTA) to be similar to a
protein sequence of known
structure,
comparative protein modelling
may be used to predict the
tertiary structure. Otherwise,
other methods such as
protein threading or
de novo protein structure
prediction must be applied.
The results of CASP are published
[1] and are divided into
several prediction categories:
External links
CASP experiments home page
